Glacial acetic acid
inear Formula: CH3CO2H
CAS Number: 64-19-7
Molecular Weight: 60.05
General Description: Glacial acetic acid is a commonly used solvent and pH modifier in peptide synthesis and purification. It may be present as a residual process reagent. The USP standard is used to quantify acetic acid levels in peptide APIs and assess formulation stability.
The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Grade: Pharmaceutical primary standard
Agency: USP
Vapor Density: 2.07 (vs air)
API Family: Glacial acetic acid
Form: Liquid
Autoignition Temperature: 800 °F
Explosion Limits: 16%, 92 °F; 4%, 59 °F
Manufacturer/Tradename: USP
Techniques: Gas chromatography (GC): suitable
Refractive Index: n20/D 1.371 (lit.)
Boiling Point: 117–118 °C (lit.)
Melting Point: 16.2 °C (lit.)
Density: 1.04 g/mL at 25 °C (lit.)
Applications: USP Biologics, pharmaceutical (small molecule), pharmaceutical
Format: Neat
